## ----message=FALSE------------------------------------------------------------ library(campsis) ## ----------------------------------------------------------------------------- model <- model_suite$pk$`2cpt_fo` ## ----------------------------------------------------------------------------- dataset <- Dataset(10) %>% add(Bolus(time=0, amount=1000, ii=24, addl=2)) %>% add(Observations(times=seq(0,72, by=1))) ## ----message=F---------------------------------------------------------------- results <- model %>% simulate(dataset, seed=1) head(results) ## ----get_started_spaguetti_plot, fig.align='center', fig.height=4, fig.width=8---- spaghettiPlot(results, "CONC") ## ----get_started_shaded_plot, fig.align='center', fig.height=4, fig.width=8---- shadedPlot(results, "CONC") ## ----get_started_2arms_plot, fig.align='center', fig.height=4, fig.width=8, message=F---- # First treatment arm arm1 <- Arm(subjects=50, label="1000 mg QD") %>% add(Bolus(time=0, amount=1000, ii=24, addl=2)) %>% add(Observations(times=seq(0,72, by=1))) # Second treatment arm arm2 <- Arm(subjects=50, label="2000 mg QD") %>% add(Bolus(time=0, amount=2000, ii=24, addl=2)) %>% add(Observations(times=seq(0,72, by=1))) dataset <- Dataset() %>% add(c(arm1, arm2)) results <- model %>% simulate(dataset, seed=1) shadedPlot(results, "CONC", colour="ARM")