Package: PMAPscore
Type: Package
Title: Identify Prognosis-Related Pathways Altered by Somatic Mutation
Version: 0.1.1
Authors@R: c(person(given = "Junwei", family = "Han", email = "hanjunwei1981@163.com", role  = c("aut", "cre", "cph")),
             person(given = "Yalan", family = "He", role  = "aut"),person(given = "Xiangmei", family = "Li", role  = "aut"))
Maintainer: Junwei Han <hanjunwei1981@163.com>
Description: We innovatively defined a pathway mutation accumulate perturbation score (PMAPscore) to reflect the position and the cumulative effect of the genetic mutations at the pathway level. Based on the PMAPscore of pathways, identified prognosis-related pathways altered by somatic mutation and predict immunotherapy efficacy by constructing a multiple-pathway-based risk model (Tarca, Adi Laurentiu et al (2008) <doi:10.1093/bioinformatics/btn577>).
License: GPL (>= 2)
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.2
Imports: base, clusterProfiler, glmnet, graphics, grDevices, maftools,
        org.Hs.eg.db, pROC, stats, survival, survminer, utils
VignetteBuilder: knitr
Depends: R (>= 4.1.0)
Suggests: knitr, rmarkdown
NeedsCompilation: no
Packaged: 2022-04-12 07:34:51 UTC; DELL
Author: Junwei Han [aut, cre, cph],
  Yalan He [aut],
  Xiangmei Li [aut]
Repository: CRAN
Date/Publication: 2022-04-12 08:12:37 UTC
Built: R 4.6.0; ; 2025-12-07 05:53:31 UTC; windows
